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Smoking has many adverse effects in men and in women, but this particular effect of nicotine on the reduction of estrogen production in woman was not known before, says Professor Wim van den Brink, Emeritus Professor of Psychiatry and Addiction from the Academic Medical Center at the University of Amsterdam, who did not take part in the research

It can contribute to the development of other cardiovascular diseases (CVDs) such as atherosclerosis, stroke, heart failure, and heart attack

Dec 31 2018;12(12):CD012173

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[2] Dip the clean rag into the soapy solution, wring out excess water, and wipe it over the soot in a smooth, straight line